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Liechty E, Hren A, Kramer L, Donovan G, Friedman A, Shirts MR, and Fox JM (2023). Analysis of Neutral Mutational Drift in an Allosteric Enzyme.
Protein Science.
32
(
8
):e4719
Mains K and Fox JM (2023).
Ketosynthase mutants enable short-chain fatty acid biosynthesis in E. coli.
Metabolic Engineering
.
77, 118-127
Kramer L, Sarkar A, Foderaro T, Markley A, Lee J, Edstrom H, Gill E, Traylor M, and Fox JM (2023).
Genetically Encoded Detection of Biosynthetic Protease Inhibitors
.
ACS Synthetic Biology.
12 (
1)
, 83–94.
Friedman AJ, Liechty ET, Kramer L, Sarkar A, Fox JM, and Shirts MR (2022).
Allosteric inhibition of PTP1B by a nonpolar terpenoid
.
J. Phys. Chem. B.
126, 42, 8427–8438.
Peoples J, Ruppe S, Mains K, and Fox JM (2022).
A Kinetic Framework for Modeling Oleochemical Biosynthesis in E. coli
.
Biotechnology and Bioengineering.
119, 3149–3161.
Sarkar A, Markley AL, Lee J, Traylor M, and Fox JM (2022).
Evolution-Guided Biosynthesis of Terpenoid Inhibitors
.
ACS Synthetic Biology.
11 (9), 3015-3027.
Mains K, Peoples J, Fox JM (2022).
Kinetically Guided, Ratiometric Tuning of Fatty Acid Biosynthesis
.
Me
tabolic Engineering.
69, 209-220.
Hongdusit A
*
, Liechty ET
*
, and Fox JM (2021).
Analysis of Three Architectures for Controlling PTP1B with Light
.
ACS Synthetic Biology.
11 (1), 61-68.
Sarkar A, Kim EY, Jang T, Hongdusit A, Kim H, Choi JM, and Fox JM (2021).
Microbially Guided Discovery and Biosynthesis of Biologically Active Natural Products
.
ACS Synthetic Biology
10 (6), 1505–1519.
Hongdusit A and Fox JM (2021).
Optogenetic Analysis of Allosteric Control in Protein Tyrosine Phosphatases
.
Biochemistry.
60 (4),
254–258
.
Ruppe A*, Mains K*, and Fox JM (2020).
A Kinetic Rationale for Functional Redundancy in Fatty Acid Biosynthesis
.
Proc. Natl. Acad. Sci. U.S.A
.,
117 (38) 23557-23564.
Hongdusit A*, Liechty E*, and Fox JM (2020).
Optogenetic Interrogation and Control of Cell Signaling
.
Current Opinion in Biotechnology
.
66, 195-206.
Hongdusit A, Zwart P, Sankaran B, and Fox JM (2020).
Minimally Disruptive Optical Control of Protein Tyrosine Phosphatase 1B
.
Nature Communications.
11, 788.
Ruppe A and Fox JM (2018).
Analysis of Interdependent Kinetic Controls of Fatty Acid Synthases
.
ACS Catalysis.
8 (12), 11722−11734.
Hjortness MK, Riccardi L, Hongdusit A, Zwart P, Sankaran B, De Vivo M, and Fox JM (2018).
Evolutionarily Conserved Allosteric Communication in Protein Tyrosine Phosphatases
.
Biochemistry
.
57 (45), 6443–6451.
Hjortness MK, Riccardi L, Hongdusit A, Ruppe A, Zhao M, Kim EY, Zwart P, Sankaran B, Arthanari H, Sousa MC, De Vivo M, and Fox JM (2018).
Abietane-Type Diterpenoids Inhibit Protein Tyrosine Phosphatases by Stabilizing an Inactive Enzyme Conformation
.
Biochemistry
.
57 (40), 5886-5896
Fox JM, Zhao M, Fink MJ, Kang K, and Whitesides GM (2018).
The Molecular Origin of Enthalpy/Entropy Compensation in Biomolecular Recognition
.
Annual Review of Biophysics.
47 (1), 223-250.
Fox JM, Kang K, Sastry M, Sherman W, Sankaran B, Zwart PH, and Whitesides GM (2017).
Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase
.
Angewandte Chemie International Edition.
56 (14), 3833-3837.
Semenov SN, Kraft LJ, Ainla A, Zhao M, Baghbanzadeh M, Campbell VE, Kang K, Fox JM, and Whitesides GM (2016).
Autocatalytic, bistable, oscillatory networks of biologically relevant organic reactions
.
Nature
, 537 (7622), 656-660.
Kang K, Choi J-M, Fox JM, Snyder PW, Moustakas DT, and Whitesides GM (2016).
Acetylation of Surface Lysing Groups of a Protein Alters the Organization and Composition of Its Crystal Contacts
.
Journal of Physical Chemistry B
,
120 (27), 6461-6468.
Fox JM, Kang K, Lockett MR, Baghbanzadeh M, Sherman W, Héroux A, Sastry M, Whitesides GM (2015).
Interactions between Hofmeister Anions and the Binding Pocket of a Protein
.
JACS,
137 (11), 3859-3866.
Fox JM and Whitesides GM (2015).
Warning Signals for Eruptive Events in Spreading Fires
.
Proc. Natl. Acad. Sci. U.S.A.
,
112 (8), 2378-2383. Also:
a letter to the editor
, and
our response
.
Nemiroski A, Gonidec M, Fox JM, Jean-Remy P, Turnage E, and Whitesides GM (2014).
Engineering Shadows to Fabricate Optical Metasurfaces
.
ACS Nano
,
8
(11), 11061-11070.
Fox JM, Jess P, Jambusaria RB, Moo GM, Liphardt J, Clark DS, Blanch HW (2013).
A Single-Molecule Analysis Reveals Morphological Targets for Cellulase Synergy
.
Nature Chemical Biology
,
9
(6), 356-61.
Fox JM, Levine SE, Blanch HW, and Clark DS (2012).
An Evaluation of Cellulose Saccharification and Fermentation with an Engineered
Saccharomyces cerevisiae
Capable of Cellobiose and Xylose Utilization
.
Biotechnology Journal
,
7
, 351-373.
Fox JM, Levine SE, Clark DS, and Blanch HW (2012).
Initial- and Processive-Cut Products Reveal Cellobiohydrolase Rate Limitations and Role of Companion Enzymes
.
Biochemistry
,
51
, 442-452.
Levine SE, Fox JM, Clark DS, and Blanch HW (2011).
A Mechanistic Model for Rational Design of Optimal Cellulase Mixtures
.
Biotechnology and Bioengineering
,
108
, 2561-2570.
Levine SE, Fox JM, Blanch HW, and Clark DS (2010).
A Mechanistic Model of the Enzymatic Hydrolysis of Cellulose
.
Biotechnology and Bioengineering
,
107
, 37-51.
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